Kamagra (Ajanta Pharma Ltd., Mumbai, India) is a drug for the treatment of disorders of erectile function. The method of its action is based on the stimulation of the blood vessels of the penis.

The drug is designed to restore erectile function and increase the duration of erection. As a phosphodiesterase type 5 inhibitor, Kamagra expands the blood vessels in the male genital organ. As a result, the increased blood flow helps to establish a prolonged erection.

Dosing and administration
Kamagra tablets are intended for oral consumption. The drug is prescribed in a dose of 50 mg to be taken one hour prior to sexual intercourse. Depending on the results, the dose can be reduced to 25 mg or increased to 100 mg. The maximum recommended dose is 100 mg one time per day. In elderly patients and patients with impaired renal or liver function, the recommended regimen is the same. The duration of the effect is between five hours and six hours.

Pharmacological properties
Sildenafil citrate, penetrating into the blood, binds to the enzyme cGMP-specific phosphodiesterase type 5, which is contained in the cells of the cavernous bodies of the penis, and blocks it. The drug’s use contributes to an increase in the concentration of cyclic guanine phosphate in the cells of the penis. This substance furthermore relaxes the smooth muscle cells of the cavernous bodies of the penis and increases the rush of blood. The result of this physiological process is a powerful erection.

Side effects
When taking Kamagra, slight headaches and migraines are possible, as are slight dizziness, photosensitivity and color disturbance, nasal congestion, rhinitis, small and short fever, diarrhea, rash, allergic reactions, urticaria, muscle pain, and cold and flu symptoms.

Contraindications
Kamagra is contraindicated in the following cases: deformation of the penis; leukemia; exacerbation of diseases of the gastrointestinal tract and gastric and intestinal ulcers; severe diseases of the cardiovascular system; hypersensitivity to sildenafil citrate and/or other components of the drug; simultaneous use with nitrate products; combination with medications for the treatment of erectile dysfunction; cirrhosis of the liver; severe renal failure; and in women, children, and adolescents.

Сombination with food and alcohol
Simultaneous intake of Kamagra and food disrupts the absorption of the medication’s active substance into the blood, which causes a delay in its onset and a sharp weakening of its effect. The drug should not be combined with alcohol, as it causes the summation of the vasodilating action of sildenafil citrate and ethyl alcohol and elicits cause a sharp and uncontrolled decrease in blood pressure in conjunction with the development of life-threatening complications.

Driving and working with mechanisms
In the course of numerous studies, it was proven that the drug does not violate the reaction rate when driving a vehicle and/or working with heavy machinery/equipment.